Abstract The NIH policy on sex as biological variable (SABV) emphasized the importance of sex-based differences in precision oncology. Over 50% of clinically actionable oncology genes are sex-biased, indicating differences in drug efficacy.
Introduction Acetaminophen (N-acetyl-p-aminophenol (APAP)), also known as paracetamol, is the most common over-the-counter medication taken during pregnancy to relieve fever, pain, or discomfort.1 In the USA and Europe, it was estimated that 50–65% of women reported using APAP at least once during pregnancy, with about 20% taking APAP in all three trimesters.
Abstract Fluorinated liquid crystal monomers (FLCMs) are ubiquitous in our daily life as being the units of liquid crystal displays, yet their toxicological impacts remain largely unexplored. Herein, this study presents a comprehensive investigation into the hazardous effects of 3,4-difluoro-4′-(trans-4-ethylcyclohexyl)-biphenyl (DFECB), a representative biphenyl FLCM, using in.
Abstract F53B (6:2 chlorinated polyfluorinated ether sulfonate), a substitute for perfluorooctane sulfonate (PFOS), is widely used as a chromium mist inhibitor in the electroplating industry. However, significant concern has arisen owing to its biological toxicity.
Abstract The commercial wasabi pastes commonly used for food preparation contain a homologous compound of chemosensory isothiocyanates (ITCs) that elicit an irritating sensation upon consumption. The impact of sniffing dietary alcoholic beverages on the sensation of wasabi spiciness has never been studied.
Background Sex-related differences in colorectal (CRC) incidence and mortality are well-documented. However, the impact of sex on metabolic pathways that drive cancer growth is not well understood. High expression of asparagine synthetase (ASNS) is associated with inferior survival for female CRC patients only.
Jie Zheng, Boshi Sun, Domenica Berardi, Lingeng Lu, Hong Yan, Shujian Zheng, Oladimeji Aladelokun, Yangzhouyun Xie, Yujun Cai, Krystal J. Godri Pollitt, Sajid A. Khan, Caroline H. Johnson
Miaomiao Teng, Xiaoli Zhao, Lingfeng Zhou, Hong Yan, Lihui Zhao, Jiaqi Sun, Yunxia Li, Wentao Zhu, Fengchang Wu
Ana K. Rosen Vollmar, Nicholas J.W. Rattray, Yuping Cai, Abhishek Jain, Hong Yan, Nicole C. Deziel, Antonia M. Calafat, Allen J. Wilcox, Anne Marie Z. Jukic, Caroline H. Johnson
Hong Yan, Ronan Talty, Abhishek Jain, Yuping Cai, Jie Zheng, Xinyi Shen, Engjel Muca, Philip B. Paty, Marcus W. Bosenberg, Sajid A. Khan, Caroline H. Johnson